全球顶尖双轨菌株库
每一株都可溯源、可验证

全球合作进口菌株库

动物双歧杆菌乳亚种B420 动物双歧杆菌乳亚种 HN019 嗜酸乳杆菌 NCFM 鼠李糖乳酪杆菌LGG 鼠李糖乳酪杆菌 HN001 嗜酸乳杆菌 La-14

动物双歧杆菌乳亚种B420

菌株拉丁名
Bifidobacterium animalis subsp. lactis B420
菌株形态
活性益生菌
原料来源
乳制品
临床功效
代谢健康、免疫健康、消化健康、大脑健康
临床研究数量
30项
临床人体受试者
6248人
推荐适用人群
寻求体重管理或改善代谢健康的成年人。
禁忌适用人群
免疫功能低下者、急性胰腺炎患者或术后有开放性伤口者。
健康预期功效

腰围缩小：经临床验证可减小腰围，帮助恢复孕前身材曲线；

对抗内脏脂肪堆积：直接针对因荷尔蒙衰老导致的深层腹部脂肪（内脏脂肪）增加问题；

预防更年期发福：有助于减缓腰围快速增长，并改善餐后糖耐量。

作用机制

B420菌株→ 强化肠道屏障（紧密连接）→ 降低 LPS（系统性内毒素）→ 提升 GLP-1 / PYY（饱腹感）→ 最终结果：减少内脏脂肪组织（VAT）

证据等级
证据类型 人类随机对照试验数据分析观察性研究动物实验 / 体外实验
可用性
局限性与注意事项
  • 目标人群：研究证据主要集中于超重及肥胖人群。
  • 起效周期：显著的临床效果通常需要持续摄入 3 至 6 个月。
  • 协同效应：与益生元纤维结合使用时，效果会有所增强。

Randomized controlled trial demonstrates response to a probiotic intervention for metabolic syndrome that may correspond to diet

Stanford University

Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults—Randomized Controlled Trial

DuPont Nutrition & Health

Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults

DuPont Nutrition & Health

Polydextrose with and without Bifidobacterium animalis ssp. lactis 420 drives the prevalence of Akkermansia and improves liver health in a multi-compartmental obesogenic mice study

IFF Health & Biosciences

The efficacy of probiotics and/or n-3 long-chain polyunsaturated fatty acids intervention on maternal prenatal and postnatal depressive and anxiety symptoms among overweight and obese women

University of Turku

Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial

IFF Health & Biosciences

lodine status in pregnant women and infants in Finland

University of Turku

The effect of probiotics on faecal microbiota and genotoxtic activity of faecal water in patients with atopic dermatitis: a randomized,_placebo-controlled study

Friedrich Schiller University Jena

Bifidobacterium lactis Fermented Milk Was Not Effective for Helicobacter pylori Eradication: A Prospective, Randomized, Double-Blind, Controlled Study

University of São Paulo (USP)