全球顶尖双轨菌株库
每一株都可溯源、可验证

全球合作进口菌株库

动物双歧杆菌乳亚种B420 动物双歧杆菌乳亚种 HN019 嗜酸乳杆菌 NCFM 鼠李糖乳酪杆菌LGG 鼠李糖乳酪杆菌 HN001 嗜酸乳杆菌 La-14

鼠李糖乳酪杆菌LGG

菌株拉丁名
Lacticaseibacillus rhamnosus GG
菌株形态
活性益生菌
原料来源
健康人体
临床功效
消化健康、免疫健康、代谢健康、口腔健康、孕期与婴幼儿、女性健康、大脑健康
临床研究数量
168项
临床人体受试者
11457人
推荐适用人群
压力引起的消化敏感和产后免疫支持人群；肠道相关皮肤敏感和一般性炎症平衡人群。
禁忌适用人群
免疫功能低下者或中心静脉导管患者。
健康预期功效

改善肠道通透性（减轻肠漏症状）；

减轻胃肠敏感性，支持免疫防御。

作用机制

LGG菌株 → 物理附着：通过菌毛高度黏附于肠道黏液 → 竞争性排斥：阻止病原体在肠壁定植 → 屏障强化：刺激黏蛋白产生，增强紧密连接完整性 → 结果：增强免疫弹性，减轻肠道炎症。

证据等级
证据类型 人类随机对照试验数据分析观察性研究动物实验 / 体外实验
可用性
局限性与注意事项
  • 聚焦：主要针对消化/免疫健康。
  • 稳定性：高度依赖生产质量以维持菌毛完整性，确保黏附能力。
  • 起效周期：急性消化问题数天内见效；免疫调节需要4-8周。

Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children

Harvard Medical School

An Open-label, Multicenter Study to Assess the Efficacy and Safety of a Novel Probiotic Blend in Patients with Functional Gastrointestinal Symptoms

Mayo Clinic

Formula selection for management of children with cow's milk allergy influences the rate of acquisition of tolerance: a prospective multicenter study

Johns Hopkins University

Probiotics to reduce antibiotic administration in care home residents aged 65 years and older: the PRINCESS RCT

University of Oxford

Dietary Treatment with Extensively Hydrolyzed Casein Formula Containing the Probiotic Lactobacillus rhamnosus GG Prevents the Occurrence of Functional Gastrointestinal Disorders in Children with Cow's Milk Allergy

University of Naples Federico

A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease

Massachusetts General Hospital

Successful treatment of relapsing Clostridium difficile colitis with Lactobacillus GG

Tufts University

Effect of Lactobacillus GG on intestinal integrity in Malawian children at risk of tropical enteropathy

Washington University in St. Louis

Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy

North Carolina State University

Transcriptomic Profile of Whole Blood Cells from Elderly Subjects Fed Probiotic Bacteria Lactobacillus rhamnosus GG ATCC 53103 (LGG) in a Phase I Open Label Study

University of Maryland