Lactobacillus acidophilus NCFM
Latin Name
Lactobacillus acidophilus NCFM
Form
Live Probiotic Culture
Source
Dairy
Clinically Studied Benefits
Digestive Health、Gut Comfort、Lactose Digestion、Metabolic Health、Brain Health、Skin Health
Clinical Studies
113
Clinical Human Participants
9533
Recommended Population
Bloating and "distended belly" caused by perimenopausal hormonal shifts.
Contraindicated Population
Immunocompromised patients or those with severe gut inflammation.
Target Health Outcomes
Significant reduction in Abdominal Bloating and Belly Distension.
Relief from Gastrointestinal Discomfort and improvement in bowel regularity.
Mechanism of Action
NCFM →<wbr/> Nerve Signaling: Induces μ-opioid receptors in the gut →<wbr/> Pain Modulation: Desensitizes the gut to gas pressure and distension →<wbr/> Microbiome Balance: Suppresses gas-producing bacteria →<wbr/> Result: Flat stomach (reduced bloating) and abdominal comfort.
Evidence Grade
Evidence Type
Human RCTMeta-analysisObservationalAnimal/In-vitro
Availability
Known Limitation & Uncertainties
- Specificity: Most effective for functional bloating; not a cure for chronic inflammatory diseases.
- Dose-Dependency: Optimal effects observed at 1 billion CFU/day or higher.
- Synergy: Combined intake with HN019 often yields better bloating relief.